研究実績
2019年
-
Modeling Steatohepatitis in Humans with Pluripotent Stem Cell-Derived Organoids
Ouchi R, Togo S, Kimura M, Shinozawa T, Koido M, Koike H, Thompson W, Karns RA, Mayhew CN, McGrath PS, McCauley HA, Zhang RR, Lewis K, Hakozaki S, Ferguson A, Saiki N, Yoneyama Y, Takeuchi I, Mabuchi Y, Akazawa C, Yoshikawa HY, Wells JM, Takebe T.
-
Large-Area Fluorescence and Electron Microscopic Correlative Imaging With Multibeam Scanning Electron Microscopy
Shibata S, Iseda T, Mitsuhashi T, Oka A, Shindo T, Moritoki N, Nagai T, Otsubo S, Inoue T, Sasaki E, Akazawa C, Takahashi T, Schalek R, Lichtman JW, Okano H.
-
Pericytes as a Source of Osteogenic Cells in Bone Fracture Healing
Supakul S, Yao K, Ochi H, Shimada T, Hashimoto K, Sunamura S, Mabuchi Y, Tanaka M, Akazawa C, Nakamura T, Okawa A, Takeda S, Sato S.
-
2018年
-
Cancer-secreted hsa-miR-940 induces an osteoblastic phenotype in the bone metastatic microenvironment via targeting ARHGAP1 and FAM134A
Hashimoto K, Ochi H, Sunamura S, Kosaka N, Mabuchi Y, Fukuda T, Yao K, Kanda H, Ae K, Okawa A, Akazawa C, Ochiya T, Futakuchi M, Takeda S, Sato S.
-
Recapitulation of Extracellular LAMININ Environment Maintains Stemness of Satellite Cells In Vitro
Ishii K, Sakurai H, Suzuki N, Mabuchi Y, Sekiya I, Sekiguchi K, Akazawa C.
-
-
Differentiation of Oligodendrocyte Precursor Cells from Sox10-Venus Mice to Oligodendrocytes and Astrocytes
Nobuharu Suzuki, Kaori Sekimoto, Chikako Hayashi, Yo Mabuchi, Tetsuya Nakamura, Akazawa C.
-
Sensory innervation of the anal canal and anorectal line in Hirschsprung’s disease: histological evidence from mouse models.
Takeda M, Miyahara K, Akazawa C, Lane GJ, Yamataka A.
-
Prospective isolated mesenchyme stem/stromal cells are enriched in the CD73+ -population and exhibit efficacy after transplantation.
Suto EG, Mabuchi Y, Suzuki N, Suzuki K, Ogata Y, Taguchi M, Muneta T, Sekiya I,Akazawa C.
-
Technical advantage of recombinant collagenase for isolation of muscle stem cells.
Ishii K, Suzuki N, Mabuchi Y, Sekiya I, Akazawa C.
-
Isolation of dental pulp stem cells with high osteogenic potential.
Yasui T, Mabuchi Y, Morikawa S, Onizawa K, Akazawa C, Nakagawa T, Okano H and Matsuzaki Y.
-
Semaphorin 3A expression following intestinal ischemia/reperfusion injury in Sox10-Venus mice.
Takeda M, Miyahara K, Okawada M,Akazawa C, Lane GJ, Yamataka A.
-
Notch2 Signaling Regulates the Proliferation of Murine Bone Marrow-Derived Mesenchymal Stem/Stromal Cells via c-Myc Expression.
Sato Y, Mabuchi Y, Miyamoto K, Araki D, Niibe K, Houlihan DD, Morikawa S, Nakagawa T, Nakajima T, Akazawa C, Hori S, Okano H, Matsuzaki Y.
-
Altered differentiation of enteric neural crest-derived cells from endothelin receptor-B null mouse model of Hirschsprung’s disease.
Fujiwara N, Miyahara K, Nakazawa-Tanaka N, Akazawa C, Yamataka A.
-
Not single but periodic injections of synovial mesenchymal stem cells maintain viable cells in knees and inhibit osteoarthritis progression in rats.
Ozeki N, Muneta T, Koga H, Nakagawa Y, Mizuno M, Tsuji K, Mabuchi Y, Akazawa C, Kobayashi E, Matsumoto K, Futamura K, Saito T, Sekiya I.
-
Purified Human Dental Pulp Stem Cells Promote Osteogenic Regeneration.
Yasui T, Mabuchi Y, Toriumi H, Ebine T, Niibe K, Houlihan D.D, Morikawa S, Onizawa K, Kawana H, Akazawa C, Suzuki N, Nakagawa T, Okano H, Matsuzaki Y.
-
Three- and four-dimensional analysis of altered behavior of enteric neural crest derived cells in the Hirschsprung’s disease mouse model.
Nakazawa-Tanaka N, Miyahara K, Fujiwara N, Urao M, Akazawa C, Yamataka A.
-
Purified human synovium mesenchymal stem cells as a good resource for cartilage regeneration.
Ogata Y, Mabuchi Y, Yoshida M, Suto EG, Suzuki N, Muneta T, Sekiya I, and Akazawa C.
-
Suppressive Function of Teneurin-4 in Proliferation and Differentiation of Muscle Satellite Cells for Tissue Regeneration.
Ishii K, Suzuki N, Mabuchi Y, Ito N, Fukada S, Okano H, Takeda S, and Akazawa C.
-
Additive dominant effect of a SOX10 mutation underlies a complex phenotype of PCWH.
Ito Y, Inoue N, Inoue YU, Nakamura S, Matsuda Y, Inagaki M, Ohkubo T, Asami J, Terakawa YW, Kohsaka S, Goto Y, Akazawa C Inoue T, and Inoue K.
-
Synovial mesenchymal stem cells promote meniscus regeneration augmented by an autologous achilles tendon graft in a rat partial meniscus defect model.
Ozeki N, Muneta T, Matsuta S, Koga H, Nakagawa Y, Mizuno M, Tsuji K, Mabuchi Y, Akazawa C, Kobayashi E, Saito T, Sekiya I.
-
High capacity of purified mesenchymal stem cells for cartilage regeneration.
Suto EG, Mabuchi Y, Suzuki N, Koyanagi A, Kawabata Y, Ogata Y, Ozeki Y, Muneta Y, Sekiya I, Akazawa C.
-
RILP interacts with HOPS complex via VPS41 subunit to regulate endocytic trafficking.
Lin X, Yang T, Wang S, Wang Z, Yun Y, Sun L, Zhou Y, Xu X, Akazawa C, Hong W, and Wang T.
-
Teneurin-4, a transmembrane protein, is a novel regulator that suppresses chondrogenic differentiation.
Suzuki N, Mizuniwa C, Ishii K, Nakagawa Y, Tsuji K, Muneta T, Sekiya I, and Akazawa C.
-
Abnormal neural crest innervation in Sox10-Venus mice with all-trans retinoic acid-induced anorectal malformations.
Suzuki R, Miyahara K, Murakami H, Doi T, Lane GJ, Mabuchi Y, Suzuki N, Yamataka A, and Akazawa C.
-
Teneurin-4 promotes cellular protrusion formation and neurite outgrowth through focal adhesion kinase signaling.
Suzuki N, Numakawa T, Chou J, de Vega S, Mizuniwa C, Sekimoto K, Adachi N, Kunugi H, Arikawa-Hirasawa E, Yamada Y, and Akazawa C.
-
LNGFR(+)THY-1(+)VCAM-1(hi+) cells reveal functionally distinct subpopulations in mesenchymal stem cells.
Mabuchi Y, Morikawa S, Harada S, Niibe K, Suzuki S, Renault-Mihara F, Houlihan DD, Akazawa C, Okano H, and Matsuzaki Y.
-
Laminin-1 promotes enteric nervous system development in mouse embryo.
Nakazawa N, Miyahara K, Okawada M, Yamataka A, Suzuki R, Akazawa C, Tomikawa-Ichikawa N, and Arikawa-Hirasawa E.
-
Differential cellular localization of antioxidant enzymes in the trigeminal ganglion.
Sato H, Shibata M, Shimizu T, Shibata S, Toriumi H, Ebine T, Kuroi T, Iwashita T, Funakubo M, Kayama Y, Akazawa C, Wajima K, Nakagawa T, Okano H, and Suzuki N.
-
Prospective isolation of murine and human bone marrow mesenchymal stem cells based on surface markers.
Mabuchi Y, Houlihan DD, Akazawa C, Okano H, and Matsuzaki Y.
-
SOX10 is a novel marker of acinus and intercalated duct differentiation in salivary gland tumors: a clue to the histogenesis for tumor diagnosis.
Ohtomo R, Mori T, Shibata S, Tsuta K, Maeshima AM, Akazawa C, Watabe Y, Honda K, Yamada T, Yoshimoto S, Asai M, Okano H, Kanai Y, and Tsuda H.
-
Correlation between multiple RET mutations and severity of Hirschsprung’s disease.
Ishii K, Doi T, Inoue K, Okawada M, Lane GJ, Yamataka A, and Akazawa C.
-
Anorectal neural crest derived cell behavior after the migration of vagal neural crest derived cells is surgically disrupted: implications for the etiology of Hirschsprung’s disease.
Miyahara K, Kato Y, Suzuki R, Akazawa C, Tanaka N, Koga H, Doi T, Lane GJ, and Yamataka A.
-
Teneurin-4 is a novel regulator of oligodendrocyte differentiation and myelination of small-diameter axons in the CNS.
Suzuki N, Fukushi M, Kosaki K, Doyle AD, de Vega S, Yoshizaki K, Akazawa C, Arikawa-Hirasawa E, and Yamada Y.
-
Bioluminescent system for dynamic imaging of cell and animal behavior.
Hara-Miyauchi C, Tsuji O, Hanyu A, Okada S, Yasuda A, Fukano T, Akazawa C, Nakamura M, Imamura T, Matsuzaki Y, Okano HJ, Miyawaki A, and Okano H.
-
Visualization of enteric neural crest cell migration in SOX10 transgenic mouse using time-lapse fluorescence imaging.
Miyahara K, Kato Y, Koga H, Dizon R, Lane GJ, Suzuki R, Akazawa C, and Yamataka A.
-
The dual origin of the peripheral olfactory system: placode and neural crest.
Katoh H, Shibata S, Fukuda K, Sato M, Satoh E, Nagoshi N, Minematsu T, Matsuzaki Y, Akazawa C, Toyama Y, Nakamura M, and Okano H.
-
Abnormal enteric innervation identified without histopathologic staining in aganglionic colorectum from a mouse model of Hirschsprung’s disease.
Miyahara K, Kato Y, Koga H, Lane GJ, Inoue T, Akazawa C, and Yamataka A.
-
Sox10-Venus mice: a new tool for real-time labeling of neural crest lineage cells and oligodendrocytes.
Shibata S, Yasuda A, Renault-Mihara F, Suyama S, Katoh H, Inoue T, Inoue YU, Nagoshi N, Sato M, Nakamura M, Akazawa C, and Okano H.
Anterior cruciate ligament-derived mesenchymal stromal cells have a propensity to differentiate into the ligament lineage
Yusuke Ogata, Yo Mabuchi, Kosuke Shinoda, Yuta Horiike, Mitsuru Mizuno, Koji Otabe, Eriko Grace Suto, Nobuharu Suzuki, Ichiro Sekiya, Akazawa C.